Class I agents affect Phase O.
1c's (flecainide, propafenone) do it most powerfully, so see prolonged QRS and a QT that is prolonged solely by the prolongation of the QRS.
1b's (lignocaine) and 1a's (quinidine, procainamide, disopyramide) don't do it in therapeutic doses, and neither does sotalol.
Amiodarone does.
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